Family Pairwise Search (FPS) is a method for scoring a query sequence against a family of sequences. (Note: the query "sequence" may alternatively be a sequence, a GCG profile or a BLAST checkpoint file.) FPS compares the query sequence individually ("pairwise") to each sequence in the family and then combines the pairwise scores into an overall score for the match.
This site provides access to
- a web server to allow you to use FPS to search various protein family libraries for matches to a protein sequence,
- an overview of the FPS algorithm,
- a description of the inputs and outputs for the FPS server,
- a sample output from the FPS server, and
- a release notes for FPS, and
- links to several papers about FPS, and
- the FPS source code for non-comercial use.
- COPYRIGHT information and how to license FPS for commercial use is described here.
FPS was developed by Timothy Bailey at the San Diego Supercomputer Center, and by William Grundy at the Department of Computer Science and Engineering, University of California, Santa Cruz. The FPS server is funded by the National Biomedical Computation Resource.
Please send comments and questions to Timothy Bailey at tbailey@sdsc.edu.